Where to Inject GLP-1 Medications
GLP-1 medications like Semaglutide and Tirzepatide are given as subcutaneous injections (into the fatty tissue under the skin). The most common areas to inject are:
- Stomach – Preferred site, at least 2 inches away from the belly button.
- Thighs – Front or outer area of the upper thigh.
- Upper arms – Back of the upper arm, in the soft fatty tissue.
Best Practices for Injection
- Rotate injection sites – Don’t use the exact same spot each time to avoid irritation or small lumps.
- Clean the area – Wash your hands and use an alcohol swab on the site before injecting.
- Pinch the skin if needed – Especially helpful if you have less fatty tissue.
- Insert at 90° – Push the needle in quickly and firmly for less discomfort.
- Hold for 5 seconds – After injecting, keep the needle in place briefly before removing.
Common Questions
Q: Can I inject into muscle?
A: No, always inject into the fatty layer under the skin, not the muscle.
Q: What if I see blood?
A: If blood enters the syringe, stop and try a different site.
Q: How often should I rotate sites?
A: Aim to rotate with every injection, moving between different areas of the abdomen, thigh, or arm.